Owing to pseudoexfoliation glaucoma’s prevalence and severity, gonioscopy should be performed to assess for pigment deposition and a Sampaolesi’s line. Sampaolesi line is a sign which may be observed during a clinical eye examination. During gonioscopy if an abundance of brown pigment is seen at or anterior. The Glaucomas. Volume II – Open Angle Glaucoma and Angle Closure Glaucoma. Authors; (view affiliations). Roberto Sampaolesi; Juan Roberto Sampaolesi.

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February 21, ; Glaucomz from: The pattern of iris transillumination and angle pigmentation is different see section Pigmentary Glaucoma.

This brief review will discuss the pathophysiology, clinical course and signs, differential diagnosis, and treatment strategies of this disease. The Academy uses cookies to analyze performance and provide relevant personalized content to users of our website. A resident article published in Ophthalmic Pearls will satisfy the RRC requirements for resident scholarly activity. A larger capsulorhexis should be made at the time of surgery to prevent anterior capsule opacification and contraction.

The confidence interval of the normal growth curve allows the prediction of the maximum normal axial length for any given age.

Subscriptions Wampaolesi About Contact Privacy. Pigment deposition on the trabecular meshwork and anterior segment structures is also observed in pigmentary glaucoma. Such eyes have weak zonular attachments as well, also complicating cataract surgery.

This patient presented with unilateral advanced pseudoexfoliation glaucoma OS a form of open-angle glaucomawhich is a systemic disease with the eye being the most affected organ.

The hooks may help with small pupils, and may also be placed into the capsular bag in cases with zonular laxity.


Reducing the Release of Pigment

What Is Pseudoexfoliation Syndrome? In eyes with secondary raised IOP, there may be the usual signs of glaucomatous optic neuropathy Figure 7.

He stated that he holds no financial interest in the products mentioned herein. Midperipheral iris transillumination defects occur in pigment dispersion syndrome.

Pseudoexfoliative Glaucoma

This page has been accessedtimes. However, in pigmentary glaucoma the defects are slitlike in a radial distribution of the midperipheral iris, whereas in pseudoexfoliation glaucoma the defects are more patchy and closer to the pupillary margin. The cyclopentolate provocative test in suspected or untreated open-angle glaucoma: Due to the volatile nature of this condition, patients with pseudoexfoliation glaucoma who demonstrate rising IOP should be examined every one to three months.

The higher IOP observed in pseudoexfoliation glaucoma can lead to more rapid optic nerve damage and visual field loss.

Ocular Echometry in the Diagnosis of Congenital Glaucoma | JAMA Ophthalmology | JAMA Network

Thoughts From Your Colleagues. It is very important to distinguish between the two conditions, as the treatment is different. The white, fluffy material deposited on the pupil margin, lens capsule, and angle Sampaolesi’s line is pseudoexfoliation material. Retinal vein occlusion has also been associated with pseudoexfoliation glaucoma, which is another factor making the prognosis of pseudoexfoliation glaucoma more guarded than POAG.

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Thank you Your feedback has been sent. The peripheral cloudy ring of the lens is usually only visible upon dilation.

Similar to the pathophysiology of pseudoexfoliation glaucoma, material accumulates in the trabecular meshwork, leading to progressive trabecular dysfunction and increased IOP. Aggarwal JL, Beveridge B. Reducing the release of pigment may sampaoleis the progression of these diseases and may even lead to a clearing of the trabecular meshwork.


These eyes are more likely to develop postoperative inflammation and posterior capsule opacification. Hypoxia can cause atrophy of the iris pigment epitheliumstroma, and muscles.

The middle clear zone is thought to be samapolesi by the posterior surface of the iris rubbing off the pseudoexfoliative material from the lens.

Ocular echometry in the diagnosis of congenital glaucoma.

PDS is more common in younger, myopic patients, and is often bilateral. This condition may present unilaterally and bilaterally and is known to be a major risk factor for secondary glaucma angle glaucoma. Sign in to make a comment Sign in to your personal account. Shihadeh may be reached at ; wisam97 yahoo. The blockage of trabecular spaces by pigment may also be a contributing facor for secondary glaucoma. Are you a resident? History of Present Illness: Purchase access Subscribe now.

Invest Ophthalmol Vis Sci. It glauocma important to note that more than 20 percent of patients with pseudoexfoliation syndrome have associated narrow angles; therefore, the anterior chamber depth of these patients should be assessed before dilation in order to avoid precipitating acute angle-closure glaucoma. Patients with exfoliation syndrome do not have the same response to topical corticosteroids as do chronic open angle glaucoma patients.

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