Feature: for medium temperatures > °C or frequent changes in temperature. 0 to 1 bar – 0 to 60 bar relative, 0 to 1 bar – 0 to 25 bar absolute; Medium. HART® interface; Optional explosion protection [Ex ia] according to ATEX, GOST- R, DNV; Linearity %; Turn down: ; Simple operation with rotary knob. Get this from a library! Farmacevtska tehnologija. Del 1, Praktikum. [Julijana Kristl ; Jelka Šmid-Korbar; Stanko Srčič].
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Galenska farmacija: (Farmacevtska tehnologija I) – Pavle Bohinc – Google Books
Computational fluid dynamics CFD simulations and experimental measurements of laboratory-scale Wurster coating were performed. Hydrophilic polyetilenglycol and hydrophobic meltable binder glyceryl palmitostearate were used for in situ fluidized hot melt granulation. framacevtska
Farmacevtska tehnologija: Praktikum. Del 1
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Binder content was shown to be important for narrow size distribution and goodflow properties. Granule shape was affected by interplay of binder content, binder particle size and granulation time.
Experimentally, the draft tube two-phase flow was evaluated by measuring the volume fraction of pellets within the draft tube and local particle velocities at the tehonlogija exit and by monitoring the local pressure drop fluctuations. CFD simulations were performed in a 2D axisymmetric space using the two-fluid farmacfvtska. URL – Presentation file, Visit http: A rather good agreement between the simulated and experimental results was observed and thus it can be assumeed that this particular simulation setup represents a computationally reasonable tool that provides a valuable insight into the Wurster coating process due to the impact of two-phase flow properties on the process.
The effect of the Wurster gap and fluidizing air flow rate on gas-solidflow was analyzed in both simulations and experiments.
You have to log in to leave a comment. Solid state analysis confirmed unaltered physical state of the granulate components and the absenceof interactions between the active and excipients. The aim of this study was to investigate the influence of binder content, binder particle size, granulation time and inlet air flow rate on granule sizeand tehnoloija distribution, granule shape and flowability, as well as on drug release rate.